Wednesday 7 November
10.00 Registration open
12.00 Lunch (buffet)
Session 1: LPMO-substrate interaction (Chair: Gustav Vaaje-Kolstad, Norwegian University of Life Sciences)
14.10 Leila LoLeggio (University of Copenhagen, Denmark): Insights on LPMO-substrate interactions from structural studies.
14.50 Luisa Ciano (University of York, United Kingdom): A spectroscopic investigation of protein-substrate interactions in lytic polysaccharide monooxygenases.
15.20 Gaston Courtade (Norwegian University of Life Sciences, Norway): Cellulose oxidation by a modular LPMO.
15.50-16.20: Coffee break
16.20 Zarah Forsberg (Norwegian University of Life Sciences, Norway): Modularity as a tool to harness the power of LPMOs in polysaccharide conversion.
16.50 Mirjam Kabel (Wageningen University, The Netherlands): Diversity of LPMOs in Myceliophthora thermophila C1.
17.20-18.30: Poster session
18.30-19.30: Meeting of the scientific committee
Thursday 8 November
Session 2: Mechanism and chemistry (Chair: Paul Walton, University of York)
8.40 Åsmund K. Røhr (Norwegian University of Life Sciences, Norway): Unravelling the molecular basis of the lytic polysaccharide (per)oxygenase reaction.
9.10 Finn Aachmann (Norwegian University of Life Sciences, Norway): NMR perspectives on Lytic Polysaccharide Monooxygenase.
9.40 Morten J. Bjerrum (University of Copenhagen, Denmark): Insight into the mechanism of Cu (II)-Lytic polysaccharide monooxygenase catalysed oxidation of polysaccharide.
10.10-10.50: Coffee break and group photo
10.50 Erik Hedegård (Lund University, Sweden): Molecular mechanism of lytic polysaccharide monooxygenase.
11.20 Jalila Simaan (Centre National de la Recherche Scientifique, France): Mechanism of copper-containing mono-oxygenases: insights from biomimetic and bioinspired complexes.
11.50 Filip Mollerup (Aalto University, Finland): Lytic polysaccharide monooxygenase presents a unique capacity for copper-catalysed Kirmse rearrangements in organic synthesis.
Session 3: Co-factors and electron donating systems (Chair/ Claus Felby, University of Copenhagen)
13:30 Kiyo Igarashi (University of Tokyo, Japan): Redox contribution of CDH and LPMO on lignocellulose degradation by the white-rot fungus Phanerochaete chrysosporium.
14.10 Aniko Varnai (Norwegian University of Life Sciences, Norway): The pyrroloquinoline-quinone (PQQ)-dependent quinohemoprotein pyranose dehydrogenase from Coprinopsis cinerea (CcPDH), belonging to the AA12 family, drives LPMO action.
14.40 Dejan Petrovic (Norwegian University of Life Sciences, Norway): Role of the N-terminal histidine methylation in fungal LPMOs.
15.10-15.40: Coffee break
15.40 K. Benedikt Möllers (University of Copenhagen, Denmark): Exploring light-driven biomass degradation.
16.10 David A. Russo (University of Copenhagen, Denmark): Harnessing cyanobacterial photosynthesis for light-driven biomass degradation.
16.40 Anthi Karnaouri (Lulea University, Sweden): Evaluation of different lignins as electron donors of fungal Lytic Polysaccharide Monooxygenases.
17.10-18.00: Poster session
19.30: Gala dinner
Friday 9 November
Session 4: Biological role and novel families (Chair: Bernard Henrissat, Centre National de la Recherche Scientifique)
8.40 Federico Sabbadin (University of York, United Kingdom): Exploring the biological roles of a new LPMO family from invertebrates, algae and oomycetes.
9.20 Camille F. Chastel (Institut National de la Recherche Agronomique / Institut Français du Pétrole - Energies Nouvelles, France): Characterization of a new LPMO family identified in the secretomes of Aspergillus spp.
9.50 Kristian Frandsen (Institut National de la Recherche Agronomique, France / University of Copenhagen, Denmark): The three dimensional X-ray crystal structure of LsAA9B - a Lentinus similis AA9 protein with a N-terminal Arg.
10.20-10.50: Coffee break
10.50 Aurore Labourel (Institut National de la Recherche Agronomique, France): Discovery and characterization of an atypical family of cellulose-active LPMO found in ectomycorrhizal and saprotrophic fungi.
11.20 Dennis Thiele (Duke University, United States): Copper transport and virulence driven by an LPMO in the fungal pathogen Cryptococcus neoformans.
Session 5: Biotech Applications (Chair: Katja Johnasen, University of Copenhagen)
13.10 Bernard Cathala (Institut National de la Recherche Agronomique, France): Lytic polysaccharide monooxygenases (LPMO) promote cellulose fiber defibrillation: a new tool for cellulose nanofibril production?
13.40 Morten Sørlie (Norwegian University of Life Sciences, Norway): The interplay between glycoside hydrolases and lytic polysaccharide monooxygenases to overpower the energetic barrier of recalcitrant polysaccharide degradation.
14.10 Vincent Eijsink (Norwegian University of Life Sciences, Norway): Recent insights into determinants of LPMO functionality in biomass processing.
14.50 General discussion/closing remarks
15.10 End of symposium